Menopause
Estradiol
A bioidentical estrogen FDA-approved to treat moderate-to-severe menopausal symptoms.
*Requires a Mochi Health Membership. Cost of medication not included in Mochi Health Membership Fee
Rated 4.5 / 5 based on 16,074 reviews
Results
The goals our members are reaching
Relieves Hot Flashes & Night Sweats
1
The most effective treatment for moderate to severe vasomotor symptoms of menopause.
Treats Vulvovaginal Symptoms
2
Certain estradiol formulations are FDA-approved for moderate-to-severe symptoms of vulvar and vaginal atrophy due to menopause.
Bone Loss Prevention
3
Certain estradiol formulations are FDA-approved to prevent postmenopausal osteoporosis.
Bioidentical Estrogen
4
Estradiol is chemically identical to the estrogen the body naturally produces.
Flexible Delivery Options
5
Available as a pill, patch, gel, cream, or vaginal ring depending on your needs.
Personalized Dosing
6
Lowest effective dose is used and adjusted based on symptoms and labs.
The treatment
Understanding the treatment
Active Ingredient:
Estradiol (17β-estradiol)
Estradiol is a bioidentical form of estrogen. Specific FDA-approved formulations are indicated for treating moderate-to-severe vasomotor symptoms of menopause, moderate-to-severe symptoms of vulvar and vaginal atrophy due to menopause, hypoestrogenism, and for preventing postmenopausal osteoporosis. Estradiol is available as oral tablets, transdermal patches, topical gels and sprays, vaginal creams and rings, and other forms. Women who still have a uterus must also take a progestogen to protect the uterine lining from overgrowth. Therapy is individualized based on symptoms, age, time since menopause, and personal risk factors.
Side effects
Most common: breast tenderness, nausea, bloating, headache, mood changes, and breakthrough bleeding (especially in the first few months). Less common but serious: blood clots in the legs or lungs, stroke, heart attack, gallbladder disease, and an increased risk of breast cancer with long-term combined therapy. Risks depend heavily on route, dose, age, and individual factors.
Avoid When
Personal history of breast cancer or other estrogen-sensitive cancers; history of blood clots (DVT, PE, stroke, heart attack); active liver disease; unexplained vaginal bleeding; known or suspected pregnancy; known hypersensitivity. Use caution with high blood pressure, gallbladder disease, migraine with aura, and smoking (which increases clot risk).
How it works
Getting started should feel simple
From eligibility to ongoing care, Mochi is designed to make each step clear, supportive, and easy to follow.
Personalized care
The medication is
the smaller part
Mochi pairs you with a physician, care team, pharmacist, and personalized plan designed to support your body, progress, and long-term goals over time.
Our expertise
You deserve doctors who listen
Rated 4.5 / 5 based on 16,074 reviews
Testimonials
FAQ
Everything you need to know
Dr. Roberto Valledor
Doctor certified
FAQ
01
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02
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03
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04
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