Skincare
Hydroquinone + Kojic Acid + Tretinoin
A compounded topical combining hydroquinone, kojic acid, and tretinoin, prescribed at provider discretion.
Dosage:
1/4/3/2/0.025%
Additional dosages available. Your provider will determine the appropriate dose for you.
*Requires a Mochi Health Membership. Cost of medication not included in Mochi Health Membership Fee
Results
Treatment overview
Compounded Topical
1
A combination of hydroquinone, kojic acid, and tretinoin prepared by a compounding pharmacy.
Hydroquinone — Tyrosinase Inhibitor
2
Hydroquinone inhibits tyrosinase, an enzyme involved in melanin production.
Kojic Acid — Tyrosinase Inhibitor
3
Kojic acid provides additional tyrosinase inhibition through a different mechanism.
Tretinoin — Prescription Retinoid
4
Tretinoin is a prescription topical retinoid that affects skin cell turnover.
Custom Compounded
5
Strengths are tailored to the individual under provider prescription.
Daily Sunscreen Required
6
Broad-spectrum SPF is essential during use to maintain results.
The treatment
Understanding the treatment
Active Ingredient:
Hydroquinone, Kojic acid, Tretinoin
This compounded topical combines hydroquinone, kojic acid, and tretinoin. It is prepared by a state-licensed compounding pharmacy under a prescription and is not FDA-approved as a combination product. Hydroquinone and kojic acid both inhibit tyrosinase (an enzyme involved in melanin production). Tretinoin is a prescription topical retinoid that affects skin cell turnover. Daily broad-spectrum sunscreen is essential while using this medication. Whether this preparation is appropriate, the strengths, and the duration of use are determined by your Mochi provider.
Side effects
Most common: dryness, redness, peeling, stinging, and increased sun sensitivity, especially in the first few weeks. Less common: contact dermatitis, paradoxical darkening, and with long-term hydroquinone use, exogenous ochronosis (a bluish-gray skin discoloration). Always use daily sunscreen.
Avoid When
Pregnancy or breastfeeding (especially due to tretinoin); known hypersensitivity to any ingredient; broken, eczematous, or sunburned skin; active rosacea flare. Avoid combining with strong exfoliants (AHAs, BHAs, benzoyl peroxide) initially. Long-term continuous use of hydroquinone (especially at higher strengths) is not recommended due to risk of ochronosis.
Personalized care
The medication is
the smaller part
Mochi pairs you with a physician, care team, pharmacist, and personalized plan designed to support your body, progress, and long-term goals over time.
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