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Mounjaro® or Ozempic: Which Is Better For Weight Loss?
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Weight loss
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What are the cost and insurance coverage differences between Mounjaro® and Ozempic®?
Beyond determining which medication would be best for you to meet your health goals, it’s critical to understand the costs and insurance coverage of these two medications to support any decision-making processes. Let’s breakdown the cost of Mounjaro® vs Ozempic:

What are the dosage differences between Mounjaro® and Ozempic®?
Both Mounjaro® and Ozempic® are administered as subcutaneous injections to the abdomen or thigh. There are, however, differences in the amount that can be delivered. The Ozempic® dose range is 0.25 - 2.0 mg while the Mounjaro® dose range is 2.5 - 15.0 mg.
Which is more effective?
In terms of weight loss, both Ozempic® and Mounjaro® have been shown to cause modest weight loss in people with type 2 diabetes. In clinical trials, people taking Ozempic® lost an average of 2-3% of their body weight, while those taking Mounjaro® lost an average of 3-4% of their body weight. Patients who used Ozempic® or Mounjaro® off-label for weight loss, rather than type 2 diabetes, lost more weight– on average around 10% for Ozempic and up to 15% for Mounjaro®.
Which One Should You Choose?
Choosing between Mounjaro® and Ozempic® can be based on your pSources. For example, if you prefer smaller doses, then Ozempic® might be a better choice. However, Mounjaro® has been noted to be mildly more effective in total weight loss. If your primary concern is price, Ozempic® is lower in cost than Mounjaro®. If your primary concern is side effects, Mounjaro® and Ozempic® have a very similar side effect profile primarily consisting of abdominal pain, nausea, vomiting, diarrhea, and constipation.
Consideration of rare side effects is important as you consider your own medical history. For Mounjaro®, these rare side effects include pancreatitis and possible kidney or bladder complications. Rare side effects associated with Ozempic® also include kidney problems and pancreatitis but can also exacerbate diabetic retinopathy and may cause hypoglycemia. If you have a history of any or a combination of these health problems, it would be beneficial to discuss which would be best for you with a healthcare professional.
Who is a good candidate for Ozempic® or Mounjaro® for weight loss?
Both medications are FDA approved for Type 2 diabetes and, given their profound impact on weight loss, often prescribed off-label for obesity. Patients who have a BMI over 27 with any weight related disease such as high blood pressure, high cholesterol, PCOS, cardiac conditions, may be eligible for obesity medications. Patients with a BMI over 30 are also eligible, with or without weight related conditions.
Who should not take Ozempic® or Mounjaro®?
In order to be an eligible candidate for either of these medicines, consulting a healthcare professional is highly recommended. These drugs can affect our health, and patients with chronic diseases or other health risks may be more prone to their side effects. Neither Mounjaro® or Ozempic® have been approved by the FDA for use in people with type 1 diabetes.
Patients with a history of pancreatitis should also use caution when taking GLP-1 agonist type medications like Ozempic® (Semaglutide) or Mounjaro® (Tirzepatide). If you or a family member has a history of MTC (Medullary Thyroid Carcinoma) or MEN2 disorder, you should not Ozempic® or Mounjaro®.
After proper consultation and sharing your health history with your healthcare professional, you can learn whether you are or are not an ideal candidate for these drugs.
Which should be taken if you're breastfeeding?
Ozempic® cannot be taken during pregnancy nor should it be taken if you are currently breastfeeding. The FDA notes that Mounjaro® should only be taken during pregnancy only if the benefit of taking the medication is greater than the risk it confers to the fetus. If you are unsure what this means or how it may apply to you, please consult with your physician prior to starting Mounjaro®. Currently there is not enough information to determine whether Mounjaro® can be taken while breastfeeding.
Find the Right Weight Loss Solution with Mochi Health
Overall, both Mounjaro® and Ozempic® can be effective in helping with weight loss in people with type 2 diabetes. However, the specific amount of weight loss may vary depending on a person's individual circumstances and how well they are able to stick to their treatment plan. It is important to discuss your treatment options with a healthcare provider to determine the best medication for your needs.
Picking the right medication for you is a very personal decision. You may want to consider your current health concerns, health goals, cost, and insurance coverage when deliberating between the options for weight loss. To determine which medication is best suited for your weight loss journey, please reach out to healthcare professionals for more information. If you’re still unsure of which medication is right for you or would like to jumpstart this process, you can reach out to Mochi Health for personalized support guidance in choosing the right weight loss solution.
To get started today, take this eligibility test to see if you’re eligible to join the Mochi Health program!
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