Mental Health
Bupropion
An atypical antidepressant FDA-approved for depression, seasonal affective disorder, and smoking cessation.
Dosage:
150mg
Additional dosages available. Your provider will determine the appropriate dose for you.
*Requires a Mochi Health Membership. Cost of medication not included in Mochi Health Membership Fee
Results
Treatment overview
Treats Depression
1
FDA-approved for major depressive disorder.
Seasonal Affective Disorder
2
FDA-approved for seasonal affective disorder.
Helps Quit Smoking
3
FDA-approved (as Zyban) for smoking cessation.
Component of Contrave
4
Combined with naltrexone in the FDA-approved Contrave product for chronic weight management.
Different Mechanism
5
Affects norepinephrine and dopamine activity rather than serotonin like SSRIs.
Multiple Formulations
6
Available in immediate-release, sustained-release, and extended-release forms.
The treatment
Understanding the treatment
Active Ingredient:
Bupropion hydrochloride
Bupropion is an atypical antidepressant that increases norepinephrine and dopamine activity in the brain (rather than serotonin like SSRIs). It is FDA-approved for major depressive disorder, seasonal affective disorder, and (as Zyban) smoking cessation. In combination with naltrexone in the FDA-approved product Contrave, bupropion is also approved for chronic weight management. Bupropion is typically taken earlier in the day to minimize the chance of insomnia.
Side effects
Most common: dry mouth, insomnia, headache, nausea, agitation, increased heart rate, sweating, and decreased appetite. Less common but important: increased blood pressure, anxiety or jitteriness, and — rarely — seizures (dose-dependent risk). Also: increased suicidal thoughts in young adults and rare allergic skin reactions.
Avoid When
History of seizure disorder; current or prior eating disorder (anorexia or bulimia); abrupt discontinuation of alcohol, benzodiazepines, or other sedatives; concurrent MAO inhibitors; known hypersensitivity. Use caution with hypertension, bipolar disorder, recent head injury, or kidney/liver disease.
Personalized care
The medication is
the smaller part
Mochi pairs you with a physician, care team, pharmacist, and personalized plan designed to support your body, progress, and long-term goals over time.
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